Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17868339 | 0.73 | NPC1 (0.55) | RXFP1MEN1KMT2ANPC1LMNA | |
| SCHEMBL6046937 | 0.73 | BRD4 (0.48) | RXFP1MEN1KMT2ANPC1CDK5 | |
| SCHEMBL7640806 | 0.73 | KMT2A (0.44) | RXFP1MEN1KMT2ANPC1CDK5 | |
| SCHEMBL9418310 | 0.71 | RXFP1 (0.79) | RXFP1MEN1KMT2ANPC1LMNA | |
| SCHEMBL51509 | 0.71 | RXFP1 (0.79) | RXFP1MEN1KMT2ANPC1LMNA | |
| SCHEMBL6259753 | 0.71 | RAB9A (0.51) | RXFP1MEN1KMT2ANPC1LMNA | |
| SCHEMBL5141691 | 0.70 | MAPK1 (0.67) | RXFP1MEN1KMT2ANPC1LMNA | |
| SCHEMBL1872764 | 0.70 | MAPK1 (0.67) | RXFP1MEN1KMT2ANPC1LMNA | |
| SCHEMBL30298632 | 0.70 | NPC1 (0.54) | RXFP1MEN1KMT2ANPC1CDK5 | |
| SCHEMBL13638606 | 0.70 | MEN1 (0.67) | RXFP1MEN1KMT2ANPC1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676724-B2 | Cyanoquinoline derivatives | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2017-06-13 | — | — | US | disclosed |
| US-20160185728-A1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2016-06-30 | — | — | US | disclosed |
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185728-A1 | CYANOQUINOLINE DERIVATIVES | CBR3, CYP3A4, CDK1 | RXFP1 1008/4885MEN1 1326/4885KMT2A 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.