Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GMNN | O75496 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
| ▸ | TOP1 | P11387 | 3/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17868359 | 1.00 | TSHR (0.42) | TSHRALDH1A1BLMHSD17B10GMNN | |
| SCHEMBL17313696 | 0.95 | TSHR (0.46) | TSHRALDH1A1BLMHSD17B10GMNN | |
| SCHEMBL17313694 | 0.95 | TSHR (0.46) | TSHRALDH1A1BLMHSD17B10GMNN | |
| SCHEMBL13279845 | 0.85 | CYP1A2 (0.53) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL11787779 | 0.85 | CYP1A2 (0.53) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL13280041 | 0.85 | CYP1A2 (0.53) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL31521539 | 0.85 | CYP1A2 (0.53) | TSHRBLMHSD17B10GMNNUSP2 | |
| SCHEMBL31146839 | 0.84 | — | — | |
| SCHEMBL25214228 | 0.81 | FAAH (0.52) | TSHRALDH1A1BLMHSD17B10GMNN | |
| SCHEMBL790275 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9561989-B2 | Process of asymmetric hydrogenation of ketals and acetals | DSM IP ASSETS B.V. (NL) | 2017-02-07 | — | — | US | disclosed |
| US-20160185683-A1 | PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS | DSM IP ASSETS B.V. (NL) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185683-A1 | PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS | KAT5, AKR1D1, AKR1C2 | TSHR 4715/4885ALDH1A1 110/4885BLM 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.