Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17868854 | 0.80 | PTGS1 (0.40) | GABRA1GABRB2PTGS2 | |
| SCHEMBL16953520 | 0.78 | SLC7A5 (0.39) | GABRA1GABRB2FOLH1MAP1LC3BMAP1LC3A | |
| SCHEMBL22642104 | 0.77 | SLC7A5 (0.41) | GABRA1GABRB2FOLH1SLC7A5ANPEP | |
| SCHEMBL16105770 | 0.76 | FOLH1 (0.42) | GABRA1GABRB2FOLH1SLC7A5ANPEP | |
| SCHEMBL17868855 | 0.75 | PARP1 (0.44) | — | |
| SCHEMBL16961697 | 0.74 | GABRA1 (0.44) | GABRA1GABRB2FOLH1MAP1LC3BMAP1LC3A | |
| SCHEMBL1080742 | 0.74 | CA12 (0.45) | — | |
| SCHEMBL24002275 | 0.74 | SLC7A5 (0.46) | GABRA1GABRB2FOLH1MAP1LC3BMAP1LC3A | |
| SCHEMBL9645709 | 0.72 | SLC7A5 (0.43) | FOLH1MAP1LC3BMAP1LC3ASLC7A5ANPEP | |
| SCHEMBL17868844 | 0.71 | HDAC1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160186217-A1 | METHOD FOR BIOCATALYTIC SYNTHESIS OF SUBSTITUTED OR UNSUBSTITUTED PHENYLACETIC ACIDS AND KETONES HAVING ENZYMES OF MICROBIAL STYRENE DEGRADATION | TECHNISCHE UNIVERSITAT BERGAKADEMIE FREIBERG (DE) | 2016-06-30 | — | — | US | disclosed |