Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844044 | 0.83 | FOLH1 (0.55) | SLC7A5ANPEPENPEPFOLH1EPHX1 | |
| SCHEMBL22642104 | 0.83 | SLC7A5 (0.41) | SLC7A5ANPEPENPEPFOLH1EPHX1 | |
| SCHEMBL20718624 | 0.82 | SMYD3 (0.47) | SLC7A5FOLH1LOXL2 | |
| SCHEMBL9472086 | 0.80 | EPHX1 (0.54) | EPHX1 | |
| SCHEMBL27712699 | 0.80 | LOXL2 (0.58) | FOLH1LOXL2NOS3NOS1NOS2 | |
| SCHEMBL765921 | 0.78 | FOLH1 (0.61) | ANPEPENPEPFOLH1 | |
| SCHEMBL8098358 | 0.78 | FOLH1 (0.47) | SLC7A5ANPEPENPEPFOLH1MAP1LC3B | |
| SCHEMBL4054915 | 0.78 | SLC7A5 (0.49) | SLC7A5ANPEPENPEPFOLH1EPHX1 | |
| SCHEMBL29478099 | 0.78 | SLC7A5 (0.49) | SLC7A5ANPEPENPEPFOLH1EPHX1 | |
| SCHEMBL9615921 | 0.77 | FURIN (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166434-A | Process for the preparation of aromatic-substituted unsaturated amides | ETHYL CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |