Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870147 | 1.00 | CTSK (0.53) | CTSKCTSSCA2CTSLCTSB | |
| SCHEMBL17884331 | 0.87 | CTSK (0.63) | CTSKCTSSCA2CTSLCTSB | |
| SCHEMBL17880448 | 0.83 | CTSK (0.59) | CTSKCTSSCA2CTSLCTSB | |
| SCHEMBL17880414 | 0.83 | CTSK (0.59) | CTSKCTSSCA2CTSLCTSB | |
| SCHEMBL17884299 | 0.82 | CTSK (0.58) | CTSKCTSSCA2CTSLCTSB | |
| SCHEMBL17884343 | 0.82 | CTSK (0.58) | CTSKCTSSCA2CTSLCTSB | |
| SCHEMBL17880434 | 0.82 | CTSK (0.58) | CTSKCTSSCA2CTSLCTSB | |
| SCHEMBL17884341 | 0.80 | CTSK (0.53) | CTSKCTSSCA2CTSLCTSB | |
| SCHEMBL5873406 | 0.78 | CTSK (0.65) | CTSKCTSSCA2CTSLCTSB | |
| SCHEMBL7754405 | 0.78 | CTSK (0.65) | CTSKCTSSCA2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180265547-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-09-20 | — | — | US | disclosed |
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | CTSK 194/4885CTSS 203/4885CA2 3535/4885 |
| US-20180265547-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | CTSK 194/4885CTSS 203/4885CA2 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.