Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.65 |
| ▸ | CTSS | P25774 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754405 | 1.00 | CTSK (0.65) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL5873386 | 1.00 | CTSK (0.65) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL26818255 | 0.87 | CTSS (0.67) | CTSKCTSSCA2CAPN1PSENEN | |
| SCHEMBL28969869 | 0.86 | CTSK (0.67) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL5559974 | 0.86 | CTSK (0.67) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL28969855 | 0.85 | CTSK (0.65) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL13921027 | 0.85 | CTSK (0.65) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL20046440 | 0.85 | CTSK (0.65) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL13921005 | 0.85 | CTSK (0.65) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL5873405 | 0.84 | KMT2A (0.52) | CTSKCTSSCA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045360-B2 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-05-16 | — | — | US | disclosed |
| US-20020090728-A1 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-07-11 | — | — | US | disclosed |
| WO-2001057526-A1 | METHOD FOR ANALYSIS OF REACTION PRODUCTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-08-09 | — | — | WO | disclosed |