Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | CHAT | P28329 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL17870555 | 1.00 | SNCA (0.53) | SNCAALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL16183105 | 0.98 | PTGS2 (0.53) | SNCAALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL13645988 | 0.91 | CHAT (0.53) | SNCAALDH1A1KDM4ERAB9AHPGD | |
| Iodide SCHEMBL17360021 | 0.87 | ACHE (0.60) | SNCAALDH1A1KDM4ERAB9AHPGD | |
| Iodide SCHEMBL17360078 | 0.87 | ACHE (0.60) | ALDH1A1KDM4ERAB9AHPGDCYP2C19 | |
| Iodide SCHEMBL17360079 | 0.87 | ACHE (0.60) | ALDH1A1KDM4ERAB9AHPGDCYP2C19 | |
| Iodide SCHEMBL17360023 | 0.87 | ACHE (0.60) | SNCAALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL17447274 | 0.85 | MAPT (0.60) | ALDH1A1KDM4ERAB9AHPGDCYP2C19 | |
| SCHEMBL17360043 | 0.85 | MAPT (0.58) | ALDH1A1KDM4ERAB9AHPGDCYP2C19 | |
| SCHEMBL17360041 | 0.85 | MAPT (0.58) | ALDH1A1KDM4ERAB9AHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9766468-B2 | Optical film | DONGWOO FINE-CHEM CO., LTD. (KR) | 2017-09-19 | — | — | US | disclosed |
| US-20160187663-A1 | OPTICAL FILM | DONGWOO FINE-CHEM CO., LTD. (KR) | 2016-06-30 | — | — | US | disclosed |