Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.67 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | DRD2 | P14416 | 3/20 | 0.67 |
| ▸ | DRD4 | P21917 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | SCN1A | P35498 | 3/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17874190 | 0.98 | OPRM1 (0.65) | OPRM1DRD3DRD2DRD4LMNA | |
| SCHEMBL27512095 | 0.89 | OPRM1 (0.64) | OPRM1DRD3DRD2DRD4LMNA | |
| Normethadone SCHEMBL24337 | 0.80 | OPRM1 (1.00) | OPRM1DRD3DRD2DRD4LMNA | |
| SCHEMBL24683697 | 0.79 | OPRM1 (0.54) | OPRM1DRD3DRD2DRD4LMNA | |
| SCHEMBL18994329 | 0.79 | OPRM1 (0.69) | OPRM1DRD3DRD2DRD4LMNA | |
| Normethadone SCHEMBL1649313 | 0.79 | OPRM1 (0.97) | OPRM1DRD3DRD2DRD4LMNA | |
| SCHEMBL10440077 | 0.78 | OPRM1 (0.73) | OPRM1DRD3DRD2DRD4LMNA | |
| SCHEMBL9295790 | 0.78 | CHRM3 (0.59) | OPRM1DRD3DRD2DRD4LMNA | |
| Methane SCHEMBL5604947 | 0.78 | OPRM1 (0.67) | OPRM1DRD3DRD2DRD4LMNA | |
| SCHEMBL17870651 | 0.77 | OPRM1 (0.46) | OPRM1DRD3DRD2DRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143042-A1 | SYSTEM AND METHOD FOR AEROSOL PARTICLE PRODUCTION OF SUBMICRON AND NANO STRUCTURED MATERIALS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2023-05-11 | — | — | US | disclosed |
| EP-3237373-A1 | \"A NOVEL PROCESS FOR CHIRAL RESOLUTION OF HIGHLY PURE (6R)-6-(DIMETHYLAMINO)-4,4-DIPHENYL-3-HEPTANONE FROM RACEMIC METHADONE HYDROCHLORIDE\ | Harman Finochem Limited (IN) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016103274-A1 | \"A NOVEL PROCESS FOR CHIRAL RESOLUTION OF HIGHLY PURE (6R)-6-(DIMETHYLAMINO)-4,4-DIPHENYL-3-HEPTANONE FROM RACEMIC METHADONE HYDROCHLORIDE\ | HARMAN FINOCHEM LIMITED (IN) | 2016-06-30 | — | — | WO | disclosed |