Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | GNRHR | P30968 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870766 | 0.93 | KDM4E (0.32) | CCNE2CCNE1CDK2GNRHRCYP3A4 | |
| SCHEMBL30178654 | 0.93 | KDM4E (0.32) | CCNE2CCNE1CDK2GNRHRCYP3A4 | |
| SCHEMBL30178288 | 0.88 | CNR1 (0.35) | CCNE2CCNE1CDK2CNR1CNR2 | |
| SCHEMBL30178581 | 0.82 | CCNE2 (0.34) | CCNE2CCNE1CDK2GNRHRJAK3 | |
| SCHEMBL21900258 | 0.80 | APEX1 (0.42) | CCNE2CCNE1CDK2GNRHRCYP3A4 | |
| SCHEMBL28645646 | 0.79 | CHEK1 (0.38) | GNRHRCYP3A4 | |
| SCHEMBL19873696 | 0.78 | KDM4E (0.44) | CCNE2CCNE1CDK2GNRHRCYP3A4 | |
| SCHEMBL30178432 | 0.77 | CCNE2 (0.32) | CCNE2CCNE1CDK2 | |
| SCHEMBL21900230 | 0.77 | FPR1 (0.41) | CCNE2CCNE1CDK2 | |
| SCHEMBL28641642 | 0.76 | KDM4E (0.45) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102882-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-30 | — | — | WO | disclosed |