Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293450 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KMT2ATLR4KDM4EMEN1 | |
| SCHEMBL8880070 | 0.88 | — | — | |
| SCHEMBL27310514 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL20561968 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KMT2ATLR4KDM4EMEN1 | |
| SCHEMBL19097520 | 0.81 | TP53 (0.30) | — | |
| SCHEMBL16086071 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTPPM1B | |
| SCHEMBL16086070 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTPPM1B | |
| SCHEMBL18025047 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTPPM1B | |
| SCHEMBL2292291 | 0.79 | SLC6A2 (0.37) | ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL11681662 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KMT2ATLR4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3236752-A2 | NOVEL ISOTHIAZOLAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102435-A2 | NOVEL ISOTHIAZOLAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |