SCHEMBL2292291

SCHEMBL2292291

COC(=O)C1[CH]CCCC1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 2/20 0.33
EPHX2 P34913 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP1A2 P05177 1/20 0.33
HIF1A Q16665 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM3 P20309 1/20 0.33
FKBP1A P62942 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7523174 0.94
SCHEMBL11328517 0.80 MAPT (0.37) SLC6A2SLC6A4SMN1; SMN2POLBMEN1
SCHEMBL17694210 0.79 SMN1; SMN2 (0.38) SLC6A2SLC6A4SMN1; SMN2POLBMEN1
SCHEMBL17870979 0.79 ALDH1A1 (0.41) MEN1KMT2AALDH1A1RAB9A
SCHEMBL11359743 0.79 SMN1; SMN2 (0.38) SLC6A2SLC6A4SMN1; SMN2POLBMEN1
SCHEMBL4022810 0.79 SMN1; SMN2 (0.38) SLC6A2SLC6A4SMN1; SMN2POLBMEN1
SCHEMBL2293450 0.79 ALDH1A1 (0.41) MEN1KMT2AALDH1A1RAB9A
SCHEMBL11359740 0.79 SMN1; SMN2 (0.38) SLC6A2SLC6A4SMN1; SMN2POLBMEN1
SCHEMBL4022813 0.79 SMN1; SMN2 (0.38) SLC6A2SLC6A4SMN1; SMN2POLBMEN1
SCHEMBL4931699 0.78 FABP7 (0.45) SMN1; SMN2CHRM2CHRM4CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0217243-A2 Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same SUNTORY LIMITED (JP) 1987-04-08 EP claimed
CN-112424188-A Pyridazinones as PARP7 inhibitors 里邦医疗公司 2021-02-26 CN disclosed
US-8795942-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-08-05 US disclosed
CN-101945936-B Ionomeric polyester copolymer/organoclay nanocomposites, method of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP 2014-01-22 CN disclosed
CN-101945933-B Telechelic polyester/polycarbonate/organoclay nanocomposites, and related methods and articles SABIC INNOVATIVE PLASTICS IP 2013-08-21 CN disclosed
CN-101874054-B Polyester composition with improved heat resistance SABIC INNOVATIVE PLASTICS IP 2013-04-17 CN disclosed
CN-101124282-B Optically clear polycarbonate polyester compositions SABIC INNOVATIVE PLASTICS IP 2013-01-09 CN disclosed
US-20120288796-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-11-15 US disclosed
US-20120214100-A1 RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-08-23 US disclosed
CN-101151295-B Polyarylate compositions and articles made therefrom SABIC INNOVATIVE PLASTICS IP 2012-08-15 CN disclosed
CN-101065433-A A stabilized polycarbonate polyester composition GEN ELECTRIC (US) 2007-10-31 CN disclosed
CN-101061148-A Curable formulations, cured compositions, and articles derived therefrom GEN ELECTRIC (US) 2007-10-24 CN disclosed
CN-101061181-A Method for controlling haze in an article comprising a polymer composition GEN ELECTRIC (US) 2007-10-24 CN disclosed
US-6414160-B1 REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed
CN-1036064-C Benzene derivatives having NGF production-promoting activity SANKYO CO (JP) 1997-10-08 CN disclosed
US-5643925-A COGNITION ACTIVATORS AND NERVE GROWTH FACTORS SANKYO COMPANY, LIMITED (JP) 1997-07-01 US disclosed
US-5614521-A NERVE GROWTH FACTOR SANKYO COMPANY, LIMITED (JP) 1997-03-25 US disclosed
EP-0501656-B1 New benzene derivatives having (NGF) production-promoting activity SANKYO CO (JP) 1997-01-22 EP disclosed
CN-1064273-A The new NGF that has generates the active benzene derivative of promotion SANKYO CO (JP) 1992-09-09 CN disclosed
EP-0501656-A2 New benzene derivatives having (NGF) production-promoting activity Sankyo Company Limited (JP) 1992-09-02 EP disclosed