Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22082145 | 0.85 | — | — | |
| SCHEMBL20631094 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL17870983 | 0.69 | TDP1 (0.35) | GPR35 | |
| SCHEMBL17871026 | 0.69 | GPR35 (0.36) | GPR35 | |
| SCHEMBL20907651 | 0.69 | KDM4E (0.36) | GPR35 | |
| SCHEMBL17885169 | 0.69 | TDP1 (0.31) | — | |
| SCHEMBL19682142 | 0.67 | — | — | |
| SCHEMBL2804281 | 0.63 | TDP1 (0.41) | — | |
| SCHEMBL7817846 | 0.61 | ALDH1A1 (0.48) | — | |
| SCHEMBL3869347 | 0.61 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10842152-B2 | Isothiazolo-based bicycles, processes for their preparation and their use as herbicides and/or plant growth regulators | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-11-24 | — | — | US | disclosed |
| US-10842152-B2 | Isothiazolo-based bicycles, processes for their preparation and their use as herbicides and/or plant growth regulators | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-11-24 | — | — | US | disclosed |
| EP-3464296-B1 | ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3464296-B1 | ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2020-10-14 | — | — | EP | disclosed |
| US-20200317690-A1 | NOVEL ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-08 | — | — | US | disclosed |
| US-20200317690-A1 | NOVEL ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-08 | — | — | US | disclosed |
| US-20200178532-A1 | NOVEL ISOTHIAZOLO-BASED BICYCLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-11 | — | — | US | disclosed |
| US-20200178532-A1 | NOVEL ISOTHIAZOLO-BASED BICYCLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-11 | — | — | US | disclosed |
| EP-3648606-A1 | NOVEL SUBSTITUTED ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | Bayer CropScience Aktiengesellschaft (DE) | 2020-05-13 | — | — | EP | disclosed |
| CN-111031799-A | Substituted isothiazolopyridinones, method for the production thereof and use thereof as herbicides and/or plant growth regulators | 拜耳作物科学股份公司 | 2020-04-17 | — | — | CN | disclosed |
| WO-2017207395-A1 | ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017207462-A1 | ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017207395-A1 | ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017207462-A1 | ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-07 | — | — | WO | disclosed |
| EP-3236752-A2 | NOVEL ISOTHIAZOLAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2017-11-01 | — | — | EP | disclosed |
| EP-3236753-A2 | NOVEL ISOTHIAZOLAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2017-11-01 | — | — | EP | disclosed |
| CN-107249329-A | Novel isothiazolamides, method for the production thereof and use thereof as herbicides and/or plant growth regulators | 拜耳作物科学股份公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-107205394-A | New isothiazole acid amides, its preparation method and its purposes as fungicide | 拜耳作物科学股份公司 | 2017-09-26 | — | — | CN | disclosed |
| WO-2016102435-A2 | NOVEL ISOTHIAZOLAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |
| WO-2016102420-A2 | NOVEL ISOTHIAZOLAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10842152-B2 | Isothiazolo-based bicycles, processes for their preparation and their use as herbicides and/or plant growth regulators | ING2, DDT, CBR3 | GPR35 3384/4885 |
| US-20200178532-A1 | NOVEL ISOTHIAZOLO-BASED BICYCLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | ING2, DDT, CBR3 | GPR35 3393/4885 |
| US-20200317690-A1 | NOVEL ISOTHIAZOLOPYRIDONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | ING2, DDT, IP6K1 | GPR35 4085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.