Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.34 |
| ▸ | LPL | P06858 | 3/20 | 0.34 |
| ▸ | F11 | P03951 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23294563 | 0.82 | LPL (0.47) | CA1CA2CA9ROCK1LIPG | |
| SCHEMBL29914599 | 0.82 | LPL (0.47) | CA1CA2CA9ROCK1LIPG | |
| SCHEMBL28270044 | 0.75 | PDK2 (0.47) | GSK3BALDH1A1HIF1A | |
| SCHEMBL2708516 | 0.74 | GSK3B (0.42) | CA1CA2CA9GSK3BALDH1A1 | |
| SCHEMBL19792212 | 0.74 | GSK3B (0.42) | GSK3BALDH1A1KDM4EHIF1AMAPT | |
| SCHEMBL16891264 | 0.73 | LPL (0.47) | CA1CA2CA9ROCK1LIPG | |
| SCHEMBL22859291 | 0.71 | CA12 (0.42) | CA1CA2CA9ALDH1A1LIPG | |
| SCHEMBL13855297 | 0.71 | PDK2 (0.42) | CA1CA2CA9ROCK1P4HB | |
| SCHEMBL69358 | 0.70 | LIPG (0.47) | CA1CA2CA9P4HBLIPG | |
| SCHEMBL29506426 | 0.70 | LIPG (0.47) | CA1CA2CA9P4HBLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016103232-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF HCV INHIBITOR | GRANULES INDIA LIMITED (IN) | 2016-06-30 | — | — | WO | disclosed |