SCHEMBL1787277

SCHEMBL1787277

C=C(C)C(=O)OCCCC(COC(=O)C(=C)C)OC(=O)C(=C)C

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 1/20 0.43
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11031643 0.92 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15407 0.90 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8943942 0.87 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL730445 0.87 TSHR (0.50) TSHRTHRBTDP1ALDH1A1
SCHEMBL8923921 0.85 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9121290 0.85 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8581536 0.84 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22207427 0.84 TSHR (0.56) TSHRTHRBALDH1A1
SCHEMBL27370383 0.84 TSHR (0.56) TSHRTHRBALDH1A1
SCHEMBL730808 0.84 TSHR (0.56) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265511-B1 BLEND OF DIVINYL MONOMER AND MONOETHYLENICALLY UNSATURATED MONOMER S. C. JOHNSON COMMERICAL MARKETS, INC. 2001-07-24 US claimed
US-11965094-B2 Curable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2024-04-23 US disclosed
US-20230203275-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2023-06-29 US disclosed
US-11421108-B2 Curable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2022-08-23 US disclosed
EP-3642284-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2022-06-01 EP disclosed
US-20210238416-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2021-08-05 US disclosed
EP-3710414-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2021-04-07 EP disclosed
US-20200325337-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2020-10-15 US disclosed
EP-3710414-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2020-09-23 EP disclosed
EP-3710415-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2020-09-23 EP disclosed
US-8258231-B2 Process for preparing a dispersion of a particulate solid FUJIFILM IMAGING COLORANTS LIMITED (GB) 2012-09-04 US disclosed
US-20110123716-A1 Process for Preparing a Dispersion of a Particulate Solid FUJIFILM IMAGING COLORANTS LIMITED (GB) 2011-05-26 US disclosed
US-20040048987-A1 Process for producing hyperbranched polymers CAMPBELL J DAVID (NL) 2004-03-11 US disclosed
US-6627720-B2 Monoethylenically unsaturated monomers are polymerized with at least one multiethylenically unsaturated monomer at high temperatures by free radical polymerization in a continuous reactor, without formation of highly crosslinked gels JOHNSON POLYMER, LLC 2003-09-30 US disclosed
EP-1001998-B1 PROCESS FOR PRODUCING HYPERBRANCHED POLYMERS JOHNSON S C COMM MARKETS INC (US) 2002-11-06 EP disclosed
US-20010039316-A1 Hyperbranched polymers BASF CORPORATION 2001-11-08 US disclosed
US-6265511-B1 BLEND OF DIVINYL MONOMER AND MONOETHYLENICALLY UNSATURATED MONOMER S. C. JOHNSON COMMERICAL MARKETS, INC. 2001-07-24 US disclosed
EP-1001998-A1 PROCESS FOR PRODUCING HYPERBRANCHED POLYMERS S.C. Johnson Commercial Markets, Inc. (US) 2000-05-24 EP disclosed
US-5986020-A HEATING MONOMER MIXTURE AND FREE RADICAL CATALYST WITH MULTI UNSATURATED COMPOUNDS BASF CORPORATION 1999-11-16 US disclosed
WO-1999007754-A1 PROCESS FOR PRODUCING HYPERBRANCHED POLYMERS S.C. JOHNSON COMMERCIAL MARKETS, INC. (US) 1999-02-18 WO disclosed