Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 12/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.35 |
| ▸ | LDHB | P07195 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668597 | 0.75 | HSD17B10 (0.41) | LDHALDHBHSD17B10ALDH1A1 | |
| SCHEMBL2805456 | 0.74 | ADORA3 (0.45) | P2RX3RXRANR4A2PDE4BPDE4D | |
| SCHEMBL9784563 | 0.72 | HCAR2 (0.38) | RXRANR4A2PDE4BPDE4DADORA3 | |
| SCHEMBL31436370 | 0.70 | HCAR2 (0.41) | RXRANR4A2PDE4BPDE4DADORA3 | |
| SCHEMBL14183027 | 0.70 | ADORA3 (0.50) | PDE4DADORA3HSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL15316167 | 0.70 | PDE10A (0.44) | P2RX3PDE4BPDE4DLDHALDHB | |
| SCHEMBL28677095 | 0.68 | FASN (0.39) | LDHALDHBHSD17B10ALDH1A1 | |
| SCHEMBL4117808 | 0.68 | FASN (0.47) | LDHALDHBHSD17B10ALDH1A1 | |
| SCHEMBL31643874 | 0.68 | FASN (0.39) | LDHALDHBHSD17B10ALDH1A1 | |
| SCHEMBL4126384 | 0.68 | CYP3A4 (0.56) | LDHALDHBHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |