SCHEMBL17874342

SCHEMBL17874342

COc1cc(N=C=O)ccc1OCCCOc1ccc(N=C=O)cc1OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.49
PRSS1 P07477 4/20 0.45
HPGD P15428 6/20 0.42
CYP3A4 P08684 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 5/20 0.42
CYP2C9 P11712 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
CYP1A2 P05177 3/20 0.42
CYP2C19 P33261 3/20 0.42
NPSR1 Q6W5P4 1/20 0.42
LMNA P02545 2/20 0.41
HSP90AA1 P07900 1/20 0.41
HTT P42858 1/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17027575 0.87 MAPT (0.50) FDPSHPGDCYP3A4ALDH1A1TDP1
SCHEMBL19755202 0.87 MAPT (0.39) FDPSPRSS1HPGDCYP3A4ALDH1A1
SCHEMBL307695 0.86 HTR3E (0.53) HPGDCYP3A4ALDH1A1TDP1MAPT
SCHEMBL29600721 0.86 HTR3E (0.53) HPGDCYP3A4ALDH1A1TDP1MAPT
SCHEMBL17880576 0.83 CYP3A4 (0.40) FDPSHPGDCYP3A4ALDH1A1TDP1
SCHEMBL1493051 0.80 CYP3A4 (0.47) HPGDCYP3A4ALDH1A1TDP1CYP1A2
SCHEMBL17874339 0.80 SMN1; SMN2 (0.47) HPGDCYP3A4ALDH1A1TDP1MAPT
SCHEMBL12924996 0.78 KDM4E (0.43) CYP3A4ALDH1A1TDP1SMN1; SMN2CYP1A2
SCHEMBL10827257 0.78 CYP3A4 (0.44) HPGDCYP3A4ALDH1A1TDP1MAPT
SCHEMBL893938 0.78 CYP3A4 (0.49) HPGDCYP3A4ALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9950996-B2 Bio-based aromatic diisocyanates for preparation of polyurethanes COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-04-24 US disclosed
US-20170369427-A1 BIO-BASED AROMATIC DIISOCYANATES FOR PREPARATION OF POLYURETHANES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-12-28 US disclosed
WO-2016103283-A1 BIO-BASED AROMATIC DIISOCYANATES FOR PREPARATION OF POLYURETHANES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170369427-A1 BIO-BASED AROMATIC DIISOCYANATES FOR PREPARATION OF POLYURETHANES PAH, ALKBH3, AOC3 FDPS 221/4885PRSS1 2114/4885HPGD 407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.