SCHEMBL307695

SCHEMBL307695

COc1ccc(N=C=O)cc1OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 1/20 0.53
HTR3B O95264 1/20 0.53
HTR3A P46098 1/20 0.53
HTR3D Q70Z44 1/20 0.53
HTR3C Q8WXA8 1/20 0.53
PTGS2 P35354 3/20 0.51
PTGS1 P23219 2/20 0.51
CYP3A4 P08684 4/20 0.50
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
HPGD P15428 1/20 0.50
TRPA1 O75762 1/20 0.48
TSHR P16473 4/20 0.47
MAPK1 P28482 2/20 0.47
CA2 P00918 3/20 0.43
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29600721 1.00 HTR3E (0.53) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL893938 0.86 CYP3A4 (0.49) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL17874342 0.86 FDPS (0.49) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL31711475 0.86 CYP3A4 (0.42) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL17027575 0.86 MAPT (0.50) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL11184869 0.85 TSHR (0.54) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL543088 0.85 CYP3A4 (0.71) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL29800238 0.85 CYP3A4 (0.71) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL124245 0.85 CYP3A4 (0.59) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL29510769 0.85 CYP3A4 (0.59) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116445053-B Preparation method of strong-binding high-corrosion-resistance coating 浙江飞鲸新材料科技股份有限公司 2024-07-09 CN claimed
CN-116445053-A Preparation method of strong-binding high-corrosion-resistance coating 浙江飞鲸新材料科技股份有限公司 2023-07-18 CN claimed
CN-114068065-B Conductive material for temperature sensor and use thereof 杭州安誉科技有限公司 2022-07-08 CN claimed
CN-114068065-A Conductive material for temperature sensor and use thereof 杭州安誉科技有限公司 2022-02-18 CN claimed
CN-112967834-A Conductive material for temperature sensor and use thereof 杭州安誉科技有限公司 2021-06-15 CN claimed
CN-112321523-B Preparation method and application of oxazolone compound capable of inhibiting bacteria in patient care process 河南科技大学第一附属医院 2021-04-30 CN claimed
CN-112321523-A Preparation method and application of oxazolone compound capable of inhibiting bacteria in patient care process 河南科技大学第一附属医院 2021-02-05 CN claimed
CN-111559985-A Oxazolone compound with bactericidal effect and preparation method thereof 河南科技大学第一附属医院 2020-08-21 CN claimed
WO-2026105118-A1 COMPOUNDS USABLE AS MODULATORS OF PERK ACTIVITY RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2026-05-21 WO disclosed
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
US-12338226-B2 Substituted benzodiazoles and use thereof in therapy THOMAS HELLEDAYS STIFTELSE FOR MEDICINSK FORSKNING (SE) 2025-06-24 US disclosed
EP-3774961-B1 ADDUCTS OF AMINE CATALYSTS FOR PRODUCING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2025-01-15 EP disclosed
WO-2024236000-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-11-21 WO disclosed
EP-4464727-A1 ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
US-4098788-A Process for preparing quinazolines BRISTOL-MYERS COMPANY (US) 1978-07-04 US disclosed
US-4088766-A PRODUCTION OF PROSTAGLANDINS IN MAMMALS THE UPJOHN COMPANY (US) 1978-05-09 US disclosed
US-4046909-A Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants MCNEIL LABORATORIES, INCORPORATED (US) 1977-09-06 US disclosed
US-4001256-A PROSTAGLANDIN PRODUCTION IN MAMMALS THE UPJOHN COMPANY (US) 1977-01-04 US disclosed
US-3998958-A Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants MCNEIL LABORATORIES, INCORPORATED (US) 1976-12-21 US disclosed
US-3991064-A Benzonaphthyridines WARNER-LAMBERT COMPANY (US) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12338226-B2 Substituted benzodiazoles and use thereof in therapy XDH, CYP11B2, CYP4X1 HTR3E 972/4885HTR3B 763/4885HTR3A 938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.