Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | SMYD3 | Q9H7B4 | 15/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13970661 | 0.84 | EPHX2 (0.50) | AHRSMYD3EPHX2 | |
| SCHEMBL1304506 | 0.83 | EPHX2 (0.59) | AHRSMYD3EPHX2 | |
| Hydrochloric Acid SCHEMBL7036109 | 0.81 | EPHX2 (0.56) | AHRSMYD3EPHX2 | |
| Hydrochloric Acid SCHEMBL7036110 | 0.81 | EPHX2 (0.56) | AHRSMYD3EPHX2 | |
| SCHEMBL3660152 | 0.80 | AHR (0.53) | AHRSMYD3EPHX2PDE3BPDE3A | |
| SCHEMBL6225349 | 0.79 | EPHX2 (0.57) | AHRSMYD3EPHX2 | |
| SCHEMBL7096246 | 0.77 | HTR1A (0.58) | AHRSMYD3EPHX2 | |
| Hydrochloric Acid SCHEMBL6447830 | 0.76 | SMYD3 (0.50) | AHRSMYD3EPHX2PDE3BPDE3A | |
| SCHEMBL688890 | 0.76 | TDP2 (0.61) | AHRSMYD3EPHX2PDE3BPDE3A | |
| SCHEMBL8468448 | 0.75 | SMYD3 (0.52) | AHRSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3037419-A1 | COMPOSITIONS OF KINASE INHIBITORS AND THEIR USE FOR TREATMENT OF CANCER AND OTHER DISEASES RELATED TO KINASES | Boston Biomedical, Inc. (US) | 2016-06-29 | — | — | EP | disclosed |