Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19395164 | 0.94 | GPR3 (0.48) | ALOX5ALDH1A1MAPK1GPR3PIM3 | |
| SCHEMBL30513581 | 0.94 | GPR3 (0.48) | ALOX5ALDH1A1MAPK1GPR3PIM3 | |
| SCHEMBL15836021 | 0.85 | GPR3 (0.58) | ALOX5ALDH1A1MAPK1GPR3PIM3 | |
| SCHEMBL15855169 | 0.85 | GPR3 (0.58) | ALOX5ALDH1A1MAPK1GPR3PIM3 | |
| SCHEMBL16582762 | 0.85 | GPR3 (0.58) | ALOX5ALDH1A1MAPK1GPR3PIM3 | |
| SCHEMBL15855442 | 0.85 | GPR3 (0.58) | ALOX5ALDH1A1MAPK1GPR3PIM3 | |
| SCHEMBL15835995 | 0.85 | GPR3 (0.58) | ALOX5ALDH1A1MAPK1GPR3PIM3 | |
| SCHEMBL15855168 | 0.85 | GPR3 (0.58) | ALOX5ALDH1A1MAPK1GPR3PIM3 | |
| SCHEMBL15855164 | 0.85 | GPR3 (0.58) | ALOX5ALDH1A1MAPK1GPR3PIM3 | |
| SCHEMBL15836006 | 0.85 | GPR3 (0.58) | ALOX5ALDH1A1MAPK1GPR3PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016102413-A1 | PROCESS FOR THE MANUFACTURE OF SPIRODIBENZOSUBERANE COMPOUNDS | SOLVAY SA (BE) | 2016-06-30 | — | — | WO | disclosed |
| EP-3037413-A1 | Process for the manufacture of dibenzosuberane compounds | Solvay SA (BE) | 2016-06-29 | — | — | EP | disclosed |