SCHEMBL15835995

SCHEMBL15835995

c1cc(-c2ccc3sc4ccccc4c3c2)cc(-c2ccc3sc4ccc(-c5ccc6sc7ccccc7c6c5)cc4c3c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.58
ALDH1A1 P00352 6/20 0.47
MAPT P10636 5/20 0.47
RAB9A P51151 3/20 0.47
HPGD P15428 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
ALOX5 P09917 1/20 0.44
PIM3 Q86V86 1/20 0.43
CYP1A2 P05177 1/20 0.42
KDM4E B2RXH2 2/20 0.42
PTPN7 P35236 1/20 0.41
DUSP3 P51452 1/20 0.41
PTPN12 Q05209 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41
LIMK1 P53667 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TNKS O95271 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15855169 1.00 GPR3 (0.58) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL15836006 1.00 GPR3 (0.58) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL15836021 1.00 GPR3 (0.58) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL16582762 1.00 GPR3 (0.58) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL15836018 1.00 GPR3 (0.58) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL15855168 1.00 GPR3 (0.58) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL15855442 1.00 GPR3 (0.58) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL15855164 1.00 GPR3 (0.58) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL15836056 0.98 GPR3 (0.56) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL15836059 0.98 GPR3 (0.56) GPR3ALDH1A1MAPTRAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-11535637-B2 Compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2022-12-27 US disclosed
US-20200216475-A1 COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2020-07-09 US disclosed
US-9978952-B2 Fused heterocyclic aromatic derivative, organic electroluminescence element material, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-22 US disclosed
US-9978952-B2 Fused heterocyclic aromatic derivative, organic electroluminescence element material, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-22 US disclosed
EP-2757101-A1 FUSED HETEROCYCLIC AROMATIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME Idemitsu Kosan Co., Ltd (JP) 2014-07-23 EP disclosed
US-20140175419-A1 FUSED HETEROCYCLIC AROMATIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-06-26 US disclosed
US-20140175419-A1 FUSED HETEROCYCLIC AROMATIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 GPR3 3681/4885ALDH1A1 196/4885MAPT 1926/4885
US-11535637-B2 Compound and organic light emitting element comprising same NR2E3, NR4A2, NR2C2 GPR3 430/4885ALDH1A1 1206/4885MAPT 3576/4885
US-20200216475-A1 COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME NR2E3, NR4A2, NR4A1 GPR3 219/4885ALDH1A1 1241/4885MAPT 4066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.