Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046955 | 0.94 | MAPT (0.49) | PLA2G2APLA2G4AALOX5ALDH1A1NPC1 | |
| SCHEMBL30513484 | 0.94 | MAPT (0.49) | PLA2G2APLA2G4AALOX5ALDH1A1NPC1 | |
| SCHEMBL18655626 | 0.86 | ALOX5 (0.50) | PLA2G2APLA2G4APLA2G10ALOX5ALDH1A1 | |
| SCHEMBL804535 | 0.85 | PLA2G2A (0.57) | PLA2G2APLA2G4APLA2G10ALOX5ALDH1A1 | |
| SCHEMBL15836011 | 0.85 | PLA2G2A (0.57) | PLA2G2APLA2G4APLA2G10ALOX5ALDH1A1 | |
| SCHEMBL15855170 | 0.85 | PLA2G2A (0.57) | PLA2G2APLA2G4APLA2G10ALOX5ALDH1A1 | |
| SCHEMBL15855167 | 0.85 | PLA2G2A (0.57) | PLA2G2APLA2G4APLA2G10ALOX5ALDH1A1 | |
| SCHEMBL15836068 | 0.85 | PLA2G2A (0.57) | PLA2G2APLA2G4APLA2G10ALOX5ALDH1A1 | |
| SCHEMBL15855190 | 0.85 | PLA2G2A (0.57) | PLA2G2APLA2G4APLA2G10ALOX5ALDH1A1 | |
| SCHEMBL15855182 | 0.85 | PLA2G2A (0.57) | PLA2G2APLA2G4APLA2G10ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016102413-A1 | PROCESS FOR THE MANUFACTURE OF SPIRODIBENZOSUBERANE COMPOUNDS | SOLVAY SA (BE) | 2016-06-30 | — | — | WO | disclosed |
| EP-3037413-A1 | Process for the manufacture of dibenzosuberane compounds | Solvay SA (BE) | 2016-06-29 | — | — | EP | disclosed |