Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875320 | 0.87 | DGAT1 (0.57) | DGAT1 | |
| SCHEMBL14062050 | 0.84 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL17875334 | 0.80 | DGAT1 (0.52) | DGAT1 | |
| SCHEMBL17875322 | 0.80 | DGAT1 (0.70) | DGAT1 | |
| SCHEMBL15749093 | 0.80 | DGAT1 (0.77) | DGAT1 | |
| SCHEMBL17875335 | 0.80 | DGAT1 (0.61) | DGAT1 | |
| SCHEMBL17875307 | 0.79 | DGAT1 (0.49) | DGAT1 | |
| SCHEMBL17875352 | 0.78 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL17875332 | 0.78 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL17875306 | 0.77 | DGAT1 (0.49) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710013-B1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2016-06-29 | — | — | EP | disclosed |