Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875306 | 0.95 | DGAT1 (0.49) | DGAT1 | |
| SCHEMBL17875348 | 0.86 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL17875334 | 0.85 | DGAT1 (0.52) | DGAT1 | |
| SCHEMBL17875304 | 0.83 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL14061973 | 0.83 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL17875318 | 0.81 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL17875307 | 0.81 | DGAT1 (0.49) | DGAT1 | |
| SCHEMBL17875315 | 0.79 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL17875351 | 0.78 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL14061813 | 0.78 | DGAT1 (0.70) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710013-B1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2016-06-29 | — | — | EP | disclosed |