Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875362 | 0.82 | GRIN2D (0.41) | NOS3NOS1MAPTGAAKDM4E | |
| SCHEMBL17875363 | 0.78 | KMT2A (0.47) | KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL15312987 | 0.78 | MAPT (0.56) | NOS3NOS1MAPTGAAKDM4E | |
| SCHEMBL15312985 | 0.78 | MAPT (0.56) | NOS3NOS1MAPTGAAKDM4E | |
| SCHEMBL5681448 | 0.78 | MAPT (0.56) | NOS3NOS1MAPTGAAKDM4E | |
| SCHEMBL15312983 | 0.78 | MAPT (0.56) | NOS3NOS1MAPTGAAKDM4E | |
| SCHEMBL5681453 | 0.78 | MAPT (0.56) | NOS3NOS1MAPTGAAKDM4E | |
| SCHEMBL5032773 | 0.69 | NOS1 (0.54) | NOS3NOS1MAPTKDM4ESIGMAR1 | |
| SCHEMBL5892472 | 0.69 | GRIN2D (0.56) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2268385 | 0.66 | KMT2A (0.45) | LMNASMN1; SMN2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3037409-A1 | BIMETALLIC CATALYST FOR OLEFIN POLYMERIZATION | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2016-06-29 | — | — | EP | disclosed |