Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681453 | 1.00 | MAPT (0.56) | MAPTKDM4EHPGDGAATDP1 | |
| SCHEMBL5681448 | 1.00 | MAPT (0.56) | MAPTKDM4EHPGDGAATDP1 | |
| SCHEMBL15312987 | 1.00 | MAPT (0.56) | MAPTKDM4EHPGDGAATDP1 | |
| SCHEMBL15312983 | 1.00 | MAPT (0.56) | MAPTKDM4EHPGDGAATDP1 | |
| SCHEMBL14962067 | 0.81 | MAPT (0.59) | MAPTKDM4EHPGDGAATDP1 | |
| SCHEMBL26051008 | 0.81 | NOS1 (0.47) | MAPTKDM4EHPGDGAATDP1 | |
| SCHEMBL5838724 | 0.81 | GRIN2D (0.54) | MAPTKDM4EHPGDGAATDP1 | |
| SCHEMBL5838730 | 0.81 | GRIN2D (0.54) | MAPTKDM4EHPGDGAATDP1 | |
| SCHEMBL17875362 | 0.80 | GRIN2D (0.41) | MAPTKDM4EHPGDGAAGRIN2D | |
| SCHEMBL17875369 | 0.78 | NOS3 (0.37) | MAPTKDM4EHPGDGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130274144-A1 | COMPOUNDS, REACTIONS, AND SCREENING METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLIOIS (US) | 2013-10-17 | — | — | US | disclosed |