SCHEMBL17875923

SCHEMBL17875923

N#Cc1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)CS(=O)(=O)Cc1ccc(-c3cc(-c4ccccc4)nc(-c4ccccc4)c3)cc1-2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
MYC P01106 1/20 0.35
ALDH1A3 P47895 2/20 0.33
PTGER4 P35408 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
JAK2 O60674 1/20 0.32
PRKD3 O94806 1/20 0.32
ABL1 P00519 1/20 0.32
EGFR P00533 1/20 0.32
ERBB2 P04626 1/20 0.32
LCK P06239 1/20 0.32
CDK1 P06493 1/20 0.32
CSF1R P07333 1/20 0.32
LYN P07948 1/20 0.32
RET P07949 1/20 0.32
KIT P10721 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877870 0.97 ABCB1 (0.35) ABCB1ABCG2MYCALDH1A3PTGER4
SCHEMBL17877844 0.96 MYC (0.36) ABCB1ABCG2MYCALDH1A3PTGER4
SCHEMBL17875913 0.90 KDM4E (0.36) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17877790 0.89 PTGDR2 (0.33) PTGER4CYP1A2CYP3A4CYP2D6TSHR
SCHEMBL17877841 0.88 PTGDR2 (0.34) PTGER4CYP1A2CYP3A4CYP2D6TSHR
SCHEMBL17875822 0.87 MYC (0.38) ABCB1ABCG2MYCALDH1A3PTGER4
SCHEMBL17875720 0.87 MYC (0.38) ABCB1ABCG2MYCALDH1A3PTGER4
SCHEMBL17875927 0.87 FLT3 (0.42) CYP1A2FLT3
SCHEMBL17875972 0.87 KDM4E (0.36) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17877678 0.87 PTGDR2 (0.34) ALKKDM4EALDH1A1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 ABCB1 3976/4885ABCG2 4711/4885MYC 2102/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ABCB1 3976/4885ABCG2 4711/4885MYC 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.