SCHEMBL1787628

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4236658	1.00	ACSL1 (0.60)	ACSL1ACSL6TTRMAPK1NPC1
	SCHEMBL13653638	0.95	TTR (0.60)	ACSL1ACSL6TTRMAPK1NPC1
	SCHEMBL1786340	0.89	TTR (0.55)	ACSL1ACSL6TTRMAPK1NPC1
	SCHEMBL1783225	0.88	TTR (0.51)	ACSL1ACSL6TTRNPC1RAB9A
	SCHEMBL1785377	0.88	RAB9A (0.53)	ACSL1ACSL6TTRNPC1RAB9A
	SCHEMBL4226088	0.85	NPC1 (0.60)	ACSL1ACSL6TTRNPC1RAB9A
	SCHEMBL12608844	0.85	TTR (0.58)	ACSL1ACSL6TTRNPC1RAB9A
	Hydrochloric Acid SCHEMBL1786756	0.84	TTR (0.56)	ACSL1ACSL6TTRNPC1RAB9A
	SCHEMBL12608847	0.83	TTR (0.53)	ACSL1ACSL6TTRNPC1RAB9A
	SCHEMBL12608817	0.81	TTR (0.51)	ACSL1ACSL6TTRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.