SCHEMBL17877625

SCHEMBL17877625

CCCC(=O)c1ccc2c(c1)C(CC)(CC)c1cc(C(C)=NOC(C)=O)ccc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 4/20 0.39
▸ HSD17B3 P37058 1/20 0.36
▸ MAPT P10636 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ RAB9A P51151 4/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ NPC1 O15118 2/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ PDE4D Q08499 4/20 0.34
▸ STS P08842 1/20 0.33
▸ PDE4B Q07343 3/20 0.33
▸ PDE4A P27815 2/20 0.33
▸ PDE4C Q08493 2/20 0.33
▸ PTGS1 P23219 2/20 0.32
▸ PTGS2 P35354 2/20 0.32
▸ MAPK14 Q16539 1/20 0.32
▸ TLK2 Q86UE8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18012642 0.91 RAB9A (0.39) MAPTMEN1KMT2ARAB9APDE4D
SCHEMBL18351201 0.86 HPGD (0.39) HPGDHSD17B3MAPTMEN1KMT2A
SCHEMBL18012774 0.85 RAB9A (0.35) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL19186354 0.85 HPGD (0.41) HPGDHSD17B3MAPTMEN1KMT2A
SCHEMBL17877624 0.84 KMT2A (0.40) HPGDMAPTMEN1KMT2ARAB9A
SCHEMBL18012785 0.83 PPARG (0.36) HSD17B3MAPTMEN1KMT2AALDH1A1
SCHEMBL17953240 0.82 PDK2 (0.45) HPGDMAPTALDH1A1NPC1NPSR1
SCHEMBL18012817 0.81 PDK2 (0.36) MAPTMEN1KMT2ARAB9APDE4D
SCHEMBL18673351 0.81 ALK (0.36) MAPTRAB9AALDH1A1NPC1SMN1; SMN2
SCHEMBL28358222 0.81 HSD17B3 (0.45) HPGDHSD17B3MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 — — US disclosed
US-9720319-B2 Colored composition, cured film, color filter, method for manufacturing color filter, solid-state imaging element, image display device, and compound FUJIFILM CORPORATION (JP) 2017-08-01 — — US disclosed
US-9720319-B2 Colored composition, cured film, color filter, method for manufacturing color filter, solid-state imaging element, image display device, and compound FUJIFILM CORPORATION (JP) 2017-08-01 — — US disclosed
US-9605154-B2 Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORPORATION (JP) 2017-03-28 — — US disclosed
US-9605154-B2 Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORPORATION (JP) 2017-03-28 — — US disclosed
US-20160376234-A1 COLORING CURABLE RESIN COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, IMAGE DISPLAY DEVICE, COMPOUND, AND CATION FUJIFILM CORPORATION (JP) 2016-12-29 — — US disclosed
US-20160216604-A1 COLORED COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2016-07-28 — — US disclosed
US-20160185969-A1 CURABLE COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGE PICKUP ELEMENT, PICTURE DISPLAY DEVICE, AND TRIARYLMETHANE COMPOUND FUJIFILM CORPORATION (JP) 2016-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376234-A1 COLORING CURABLE RESIN COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, IMAGE DISPLAY DEVICE, COMPOUND, AND CATION O60361, WDR12, SEM1 HPGD 4062/4885HSD17B3 3665/4885MAPT 1958/4885
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 HPGD 4062/4885HSD17B3 3665/4885MAPT 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback