SCHEMBL1787794

SCHEMBL1787794

CCCCCCc1c(CC)cccc1C(C(=O)O)=C(C#N)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 3/20 0.39
MCL1 Q07820 3/20 0.39
BCL2L1 Q07817 2/20 0.39
BAK1 Q16611 2/20 0.39
KAT8 Q9H7Z6 2/20 0.39
PPARA Q07869 2/20 0.39
PPARG P37231 1/20 0.39
EP300 Q09472 1/20 0.39
KAT2A Q92830 1/20 0.39
KAT2B Q92831 1/20 0.39
KAT5 Q92993 1/20 0.39
SAE1 Q9UBE0 1/20 0.39
CYSLTR2 Q9NS75 6/20 0.37
CYSLTR1 Q9Y271 6/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PLK1 P53350 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30712327 0.82 ALDH1A1 (0.43) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL475422 0.82 ALDH1A1 (0.43) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL15879449 0.81 CLCN2 (0.37) CES2CES1ALDH1A1
SCHEMBL5273351 0.79 ALDH1A1 (0.40) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL433916 0.76 KAT8 (0.55) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL343182 0.75 ALDH1A1 (0.43) BIDMCL1BCL2L1BAK1KAT8
Ammonia Solution, Strong SCHEMBL7713478 0.75 KAT8 (0.54) BIDMCL1BCL2L1BAK1KAT8
Ammonia Solution, Strong SCHEMBL7713477 0.75 KAT8 (0.54) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL2582171 0.73 CLCN2 (0.37) CES2CES1ALDH1A1
SCHEMBL11230459 0.72 BID (0.48) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3406243-B1 COMBINATION OF LICOCHALCONE A OR AN EXTRACT OF RADIX GLYCYRRHIZAE INFLATAE, COMPRISING LICOCHALCONE A, PHENOXYETHANOL AND, IF DESIRED, GLYCERIN BEIERSDORF AG (DE) 2023-02-22 EP disclosed
EP-2765145-B1 SILYLATED POLYBUTADIENE NIPPON SODA CO (JP) 2022-03-02 EP disclosed
EP-2265245-B1 COOLING COSMETIC OR DERMATOLOGICAL PREPARATIONS HAVING A CONTENT OF (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDYNE-2-YL)ETHYL-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-(CYANOMETHYL)PHENYL)-2-ISPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE FOR THE REDUCTION OF ERYTHEMA BEIERSDORF AG (DE) 2021-04-28 EP disclosed
EP-3406243-A1 COMBINATION OF LICOCHALCONE A OR AN EXTRACT OF RADIX GLYCYRRHIZAE INFLATAE, COMPRISING LICOCHALCONE A, PHENOXYETHANOL AND, IF DESIRED, GLYCERIN Beiersdorf AG (DE) 2018-11-28 EP disclosed
US-9828448-B2 Silylated polybutadiene NIPPON SODA CO., LTD. (JP) 2017-11-28 US disclosed
US-9707417-B2 Use of benzotropolone derivatives as UV absorbers and antioxidants and their use in sunscreens and/or cosmetic compositions BASF SE (DE) 2017-07-18 US disclosed
EP-1535603-B1 Cosmetic or dermatological preparation containing creatin and/or creatinin and concentrations of electrolytes of at least 50 mmol/l BEIERSDORF AG (DE) 2017-05-17 EP disclosed
EP-1485062-B1 WAX-COATED COSMETIC ACTIVE SUBSTANCE PARTICLES BEIERSDORF AG (DE) 2016-11-23 EP disclosed
EP-2296760-B1 USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS BASF SE (DE) 2016-03-16 EP disclosed
EP-1535604-B1 Combination of creatine and creatinine, phenoxyethanol and glycerine BEIERSDORF AG (DE) 2015-07-01 EP disclosed
EP-1537849-A1 Cosmetic and dermatological composition containing licochalcon A and soy been germ extract Beiersdorf AG (DE) 2005-06-08 EP disclosed
EP-1535603-A1 Cosmetic or dermatological preparation containing creatin and/or creatinin and concentrations of electrolytes of at least 50 mmol/l Beiersdorf AG (DE) 2005-06-01 EP disclosed
EP-1535605-A1 Cosmetic preparations containing creatine, creatinine and/or the derivatives thereof combined with an organic thickener. Beiersdorf AG (DE) 2005-06-01 EP disclosed
EP-1535604-A1 Combination of creatine and/or creatinine, phenoxyethanol and eventually glycerine Beiersdorf AG (DE) 2005-06-01 EP disclosed
EP-1423084-A1 COSMETIC OIL-IN-WATER PREPARATION AND USE THEREOF FOR LIGHT SKINCARE Beiersdorf AG (DE) 2004-06-02 EP disclosed
EP-1380279-A1 Cosmetic or dermatological formulation used to care for the facial skin Beiersdorf AG (DE) 2004-01-14 EP disclosed
EP-1380288-A1 Cosmetic and dermatological photoprotective compositions containing hydrophobic acrylamidomethylpropanesulphonic acid (AMPS) polymer Beiersdorf AG (DE) 2004-01-14 EP disclosed
EP-1378233-A2 Cosmetic or dermatological formulations for the care of facial skin Beiersdorf AG (DE) 2004-01-07 EP disclosed
EP-1304102-A2 Combination of retinoids and cyclodextrins in cosmetic or dermatological O/W-emulsions Beiersdorf AG (DE) 2003-04-23 EP disclosed
WO-2003017952-A1 COSMETIC OIL-IN-WATER PREPARATION AND USE THEREOF FOR LIGHT SKINCARE BEIERSDORF AG (DE) 2003-03-06 WO disclosed