SCHEMBL17877968

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11998218	0.96	L3MBTL1 (0.65)	KDM4EL3MBTL1ATMMAPK1ALDH1A1
	SCHEMBL17953780	0.95	KDM4E (0.55)	KDM4EL3MBTL1ATMMAPK1ALDH1A1
	SCHEMBL17953761	0.95	KDM4E (0.55)	KDM4EL3MBTL1ATMMAPK1ALDH1A1
	SCHEMBL17953687	0.95	KDM4E (0.55)	KDM4EL3MBTL1ATMMAPK1ALDH1A1
	SCHEMBL18561901	0.94	L3MBTL1 (0.63)	KDM4EL3MBTL1ATMMAPK1ALDH1A1
	SCHEMBL23989180	0.91	KDM4E (0.50)	KDM4EL3MBTL1ATMMAPK1ALDH1A1
	SCHEMBL17777669	0.91	KDM4E (0.50)	KDM4EL3MBTL1ATMALDH1A1KMT2A
	SCHEMBL15435976	0.89	L3MBTL1 (0.62)	KDM4EL3MBTL1ATMMAPK1ALDH1A1
	SCHEMBL17229071	0.89	L3MBTL1 (0.57)	KDM4EL3MBTL1ATMMAPK1ALDH1A1
	SCHEMBL11998227	0.89	L3MBTL1 (0.59)	KDM4EL3MBTL1ATMMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.