SCHEMBL17878490

SCHEMBL17878490

CC1(C)OB(c2cccc(-c3cccc(N(c4ccccc4)c4cccc(-c5ccccc5)c4)c3)c2)OC1(C)C

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.55
LPL P06858 13/20 0.55
P4HB P07237 1/20 0.34
DGAT1 O75907 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.33
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
PDGFRB P09619 1/20 0.32
KDR P35968 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17878513 0.99 LIPG (0.53) LIPGLPLP4HBDGAT1IRAK4
SCHEMBL20964185 0.99 LIPG (0.53) LIPGLPLP4HBDGAT1IRAK4
SCHEMBL16383444 0.97 LIPG (0.56) LIPGLPLP4HBDGAT1IRAK4
SCHEMBL31601991 0.96 LIPG (0.58) LIPGLPLP4HBDGAT1IRAK4
SCHEMBL23308389 0.94 LIPG (0.59) LIPGLPLP4HBDGAT1IRAK4
SCHEMBL30386638 0.94 LIPG (0.59) LIPGLPLP4HBDGAT1IRAK4
SCHEMBL18561843 0.93 LIPG (0.61) LIPGLPLP4HBDGAT1IRAK4
SCHEMBL22698943 0.92 LIPG (0.51) LIPGLPLP4HBDGAT1IRAK4
SCHEMBL15552944 0.91 LIPG (0.59) LIPGLPLP4HBDGAT1IRAK4
SCHEMBL30387012 0.91 LIPG (0.59) LIPGLPLP4HBDGAT1IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957441-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-01 US disclosed
US-9957441-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-01 US disclosed
US-20160190467-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190467-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160190467-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AOC2, TYR, TAAR1 LIPG 3199/4885LPL 2918/4885P4HB 4637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.