Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LAP3 | P28838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14908325 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL216743 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL216744 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL8232952 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL12053128 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL29400943 | 0.98 | ALDH1A1 (0.53) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL17389326 | 0.98 | ALDH1A1 (0.53) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL6178492 | 0.98 | ALDH1A1 (0.53) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL17389325 | 0.98 | ALDH1A1 (0.53) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 | |
| Oxalic Acid SCHEMBL3340626 | 0.97 | ALDH1A1 (0.51) | ALDH1A1SLC15A1LTA4HSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771394-B2 | Antimicrobial polymyxins for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2017-09-26 | — | — | US | disclosed |
| US-9771394-B2 | Antimicrobial polymyxins for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2017-09-26 | — | — | US | disclosed |
| US-20160185823-A1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185823-A1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | VIP, AQP1, PEF1 | ALDH1A1 4807/4885SLC15A1 489/4885LTA4H 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.