SCHEMBL17878948

SCHEMBL17878948

CC1(C)c2ccccc2-c2cc3c4ccccc4c4cc(-c5ccc(-c6nc(-c7ccccc7)nc(-n7c8ccccc8c8ccccc87)n6)cc5)ccc4c3cc21

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 0.31
▸ RXRB P28702 1/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ ATM Q13315 1/20 0.30
▸ PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17878937 0.96 RXRA (0.30) RXRARXRB
SCHEMBL16076412 0.93 MEN1 (0.30) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL17921530 0.92 MEN1 (0.34) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL16076439 0.92 MEN1 (0.31) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL16231286 0.91 NPY5R (0.32) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL17070995 0.91 — —
SCHEMBL24216248 0.90 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL30021551 0.90 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL802103 0.90 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL16521268 0.90 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160190470-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-06-30 — — US disclosed
US-20160190470-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160190470-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME EBPL, ICMT, ICOSLG RXRA 3797/4885RXRB 3450/4885MEN1 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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