Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686136 | 0.84 | SIGMAR1 (0.68) | SIGMAR1TMEM97CYP3A4HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11689691 | 0.83 | SIGMAR1 (0.66) | SIGMAR1TMEM97CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL10120597 | 0.81 | SIGMAR1 (0.56) | SIGMAR1TMEM97CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL24358373 | 0.79 | SIGMAR1 (0.61) | SIGMAR1TMEM97CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL4003175 | 0.77 | SIGMAR1 (0.52) | SIGMAR1CYP3A4HSD17B10ALDH1A1OPRL1 | |
| SCHEMBL13131259 | 0.76 | CYP2D6 (0.53) | SIGMAR1TMEM97CYP3A4ALDH1A1TSHR | |
| SCHEMBL11934569 | 0.76 | SIGMAR1 (0.56) | SIGMAR1TMEM97ALDH1A1TSHRTDP1 | |
| SCHEMBL15112286 | 0.74 | HTR1D (0.54) | SIGMAR1TMEM97ALDH1A1TSHRHRH3 | |
| SCHEMBL3837603 | 0.74 | SIGMAR1 (0.56) | SIGMAR1TMEM97CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL16084375 | 0.72 | SIGMAR1 (0.53) | SIGMAR1TMEM97CYP3A4HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111408-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY AND HUNTINGTON'S DISEASE | BIOGEN MA INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| US-20160185753-A1 | DEUTERATED DIAMINOPYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS | SUZHOU ZELGEN BIOPHARMACEUTICALS CO., LTD. (CN) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185753-A1 | DEUTERATED DIAMINOPYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS | DCK, DPYD, PDCD1 | SIGMAR1 4781/4885TMEM97 4378/4885CYP3A4 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.