Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149665 | 0.82 | KMT2A (0.64) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL14699690 | 0.82 | MEN1 (0.45) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7151326 | 0.82 | KMT2A (0.64) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL10801126 | 0.82 | KMT2A (0.64) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL12899478 | 0.81 | MEN1 (0.46) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL12929187 | 0.81 | MEN1 (0.46) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL19404701 | 0.81 | MEN1 (0.48) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL14419513 | 0.81 | MEN1 (0.48) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7145829 | 0.80 | MEN1 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7153011 | 0.80 | MEN1 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688707-B2 | Bicyclic morpholino compounds and oligomeric compounds prepared therefrom | IONIS PHARMACEUTICALS, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160186175-A1 | BICYCLIC MORPHOLINO COMPOUNDS AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | IONIS PHARMACEUTICALS, INC. (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160186175-A1 | BICYCLIC MORPHOLINO COMPOUNDS AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | HNRNPM, UPF1, METTL16 | MEN1 3624/4885KMT2A 1902/4885L3MBTL1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.