SCHEMBL17880418

CN[C@]1(C)CCCCCCC=CCCC[C@@](C)(C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(N)=O)NC(=O)[C@H](N[C@H](C=O)CC(C)C)NC(=O)[C@H](N[C@H](C=O)CC(C)C)NC(=O)[C@H](N[C@H](C=O)CCCCN)NC(=O)[C@H](N[C@H](C=O)Cc2c[nH]c3ccccc23)NC(=O)[C@H](N[C@H](C=O)CC(C)C)NC(=O)[C@H](N[C@H](C=O)CC(N)=O)NC1=O

nearest known ligand 0.54

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MDM2	Q00987	10/20	0.54

▸	MDM4	O15151	8/20	0.54

▸	BCL2A1	Q16548	1/20	0.46

▸	EIF4E	P06730	1/20	0.45

▸	EIF4EBP1	Q13541	1/20	0.45

▸	ESR1	P03372	5/20	0.44

▸	ESR2	Q92731	2/20	0.44

▸	GALR2	O43603	1/20	0.43

▸	GALR1	P47211	1/20	0.43

▸	EED	O75530	1/20	0.42

▸	PCSK9	Q8NBP7	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17880429	0.80	MDM2 (0.71)	MDM2MDM4EIF4EEIF4EBP1ESR1
SCHEMBL13227599	0.80	MDM2 (0.49)	MDM2MDM4BCL2A1EIF4EEIF4EBP1
SCHEMBL17880463	0.75	KRAS (0.48)	EIF4EEIF4EBP1ESR1
SCHEMBL17880430	0.74	MDM2 (0.78)	MDM2MDM4BCL2A1EIF4EEIF4EBP1
SCHEMBL17319579	0.74	MDM2 (0.44)	MDM2MDM4BCL2A1EEDPCSK9
SCHEMBL17884324	0.70	MDM2 (0.71)	MDM2MDM4EIF4EEIF4EBP1PCSK9
SCHEMBL29874494	0.65	ERAP2 (0.56)	—
SCHEMBL8177170	0.64	ERBB2 (0.65)	—
SCHEMBL17880462	0.64	ERBB2 (0.38)	—
SCHEMBL30262173	0.64	ERAP2 (0.56)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20160185821-A1	Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES	CALIFORNIA INSTITUTE OF TECHNOLOGY	2016-06-30	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20160185821-A1	Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES	QPCT, PTMS, MAX	MDM2 473/4885MDM4 641/4885BCL2A1 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.