Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74779 | 0.80 | ALDH1A1 (0.50) | TSHRPTPN1ALDH1A1ALOX15LMNA | |
| SCHEMBL271027 | 0.80 | ALDH1A1 (0.50) | TSHRPTPN1ALDH1A1ALOX15LMNA | |
| SCHEMBL9697277 | 0.80 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL221749 | 0.80 | ALDH1A1 (0.50) | TSHRPTPN1ALDH1A1ALOX15LMNA | |
| SCHEMBL8909670 | 0.80 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL11791908 | 0.79 | PTPN1 (0.41) | TSHRPTPN1ALDH1A1ALOX15LMNA | |
| SCHEMBL17880417 | 0.79 | PTPN1 (0.41) | TSHRPTPN1ALDH1A1ALOX15LMNA | |
| SCHEMBL11791904 | 0.79 | PTPN1 (0.41) | TSHRPTPN1ALDH1A1ALOX15LMNA | |
| SCHEMBL30902273 | 0.77 | ALDH1A1 (0.39) | TSHRPTPN1ALDH1A1ALOX15LMNA | |
| SCHEMBL23872888 | 0.77 | SMN1; SMN2 (0.50) | TSHRALDH1A1ALOX15LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | TSHR 2378/4885PTPN1 4006/4885ALDH1A1 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.