Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11791904 | 1.00 | PTPN1 (0.41) | PTPN1ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL17880417 | 1.00 | PTPN1 (0.41) | PTPN1ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL221749 | 0.83 | ALDH1A1 (0.50) | PTPN1ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL74779 | 0.83 | ALDH1A1 (0.50) | PTPN1ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL271027 | 0.83 | ALDH1A1 (0.50) | PTPN1ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL24763385 | 0.83 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL31298510 | 0.82 | PTPN1 (0.38) | PTPN1ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL5074213 | 0.80 | PTPN1 (0.34) | PTPN1ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL30902273 | 0.80 | ALDH1A1 (0.39) | PTPN1ALDH1A1ALOX15LMNAHSD17B10 | |
| SCHEMBL17880457 | 0.79 | TSHR (0.39) | PTPN1ALDH1A1ALOX15LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487149-A1 | METHOD FOR PRODUCING KETONE | JX Nippon Oil & Energy Corporation (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20120197036-A1 | METHOD FOR MANUFACTURING KETONE | OSAKA UNIVERSITY (JP) | 2012-08-02 | — | — | US | disclosed |
| US-3949007-A | METAL HYDROXIDE OR ALKOXIDE CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120197036-A1 | METHOD FOR MANUFACTURING KETONE | CBR1, CBR3, DUOX1 | PTPN1 4615/4885ALDH1A1 79/4885ALOX15 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.