Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.51 |
| ▸ | HGF | P14210 | 1/20 | 0.46 |
| ▸ | MST1R | Q04912 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17370940 | 0.90 | MET (0.48) | METAXL | |
| SCHEMBL371933 | 0.84 | MET (0.48) | METHGFMST1RAXL | |
| SCHEMBL2866395 | 0.80 | MET (0.56) | METHGFMST1R | |
| SCHEMBL372334 | 0.79 | MET (0.55) | METHGFMST1R | |
| SCHEMBL4464718 | 0.75 | MET (0.56) | METHGFMST1R | |
| SCHEMBL371903 | 0.74 | MET (0.60) | METHGFMST1R | |
| SCHEMBL15405365 | 0.73 | MET (0.54) | METHGFMST1R | |
| SCHEMBL2865336 | 0.73 | MET (0.54) | METHGFMST1RAXL | |
| SCHEMBL2866269 | 0.73 | MET (0.52) | METHGFMST1RAXL | |
| SCHEMBL377067 | 0.73 | MET (0.48) | METAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185725-A1 | c-Met Modulators and Method of Use | EXELIXIS, INC. | 2016-06-30 | — | — | US | disclosed |
| US-20160185725-A1 | c-Met Modulators and Method of Use | EXELIXIS, INC. | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185725-A1 | c-Met Modulators and Method of Use | FLT4, MET, FLT1 | MET 2/4885HGF 8/4885MST1R 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.