Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.63 |
| ▸ | ESR1 | P03372 | 4/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042862 | 0.92 | MAPK14 (0.81) | MAPK14PTGS2ESR1ESR2MAPK13 | |
| SCHEMBL18154508 | 0.88 | ESR1 (0.79) | MAPK14PTGS2ESR1ESR2MAPK13 | |
| SCHEMBL6252381 | 0.88 | ESR1 (0.79) | MAPK14PTGS2ESR1ESR2MAPK13 | |
| SCHEMBL4887669 | 0.88 | ESR1 (0.79) | MAPK14PTGS2ESR1ESR2MAPK13 | |
| SCHEMBL17274470 | 0.86 | PTGS2 (0.65) | MAPK14PTGS2ESR1ESR2MAPK13 | |
| SCHEMBL17883089 | 0.85 | PTGS2 (0.67) | MAPK14PTGS2ESR1ESR2 | |
| SCHEMBL6646016 | 0.83 | MAPK14 (1.00) | MAPK14PTGS2ESR1ESR2MAPK13 | |
| SCHEMBL6646025 | 0.83 | MAPK14 (1.00) | MAPK14PTGS2ESR1ESR2MAPK13 | |
| SCHEMBL18160179 | 0.80 | PTGS2 (0.67) | MAPK14PTGS2ESR1ESR2MAPK13 | |
| SCHEMBL6342907 | 0.78 | PTGS2 (1.00) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180006236-A1 | ORGANIC COMPOUNDS AND ELECTRONIC DEVICE COMPRISING ORGANIC LAYER COMPRISING ORGANIC COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-04 | — | — | US | disclosed |
| WO-2016101865-A1 | ORGANIC COMPOUNDS AND ELECTRONIC DEVICE COMPRISING ORGANIC LAYER COMPRISING ORGANIC COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180006236-A1 | ORGANIC COMPOUNDS AND ELECTRONIC DEVICE COMPRISING ORGANIC LAYER COMPRISING ORGANIC COMPOUNDS | OR10J3, OCIAD2, VDAC2 | MAPK14 3125/4885PTGS2 3251/4885ESR1 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.