Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 6/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715053 | 0.97 | ALOX5 (0.43) | ALOX5KDM4EATML3MBTL1PRKDC | |
| SCHEMBL20714985 | 0.96 | ALOX5 (0.43) | ALOX5KDM4EATML3MBTL1PRKDC | |
| SCHEMBL15446141 | 0.93 | ALOX5 (0.43) | ALOX5KDM4EATML3MBTL1PRKDC | |
| SCHEMBL16648210 | 0.92 | ALOX5 (0.53) | ALOX5KDM4EATML3MBTL1PRKDC | |
| SCHEMBL18804980 | 0.91 | ALOX5 (0.52) | ALOX5KDM4EATML3MBTL1PRKDC | |
| SCHEMBL10165764 | 0.91 | ALOX5 (0.54) | ALOX5KDM4EATML3MBTL1PRKDC | |
| SCHEMBL17885293 | 0.90 | ALOX5 (0.51) | ALOX5KDM4EATML3MBTL1PRKDC | |
| SCHEMBL17735751 | 0.90 | ALOX5 (0.51) | ALOX5KDM4EATML3MBTL1PRKDC | |
| SCHEMBL17735771 | 0.90 | ALOX5 (0.51) | ALOX5KDM4EATML3MBTL1PRKDC | |
| SCHEMBL18623539 | 0.90 | ALOX5 (0.51) | ALOX5KDM4EATML3MBTL1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159434-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230046046-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-02-16 | — | — | US | disclosed |
| EP-3679023-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-11-02 | — | — | EP | disclosed |
| EP-3679024-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-11-02 | — | — | EP | disclosed |
| EP-3237409-B1 | CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS | MERCK PATENT GMBH (DE) | 2022-01-05 | — | — | EP | disclosed |
| US-20190044071-A1 | CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS | MERCK PATENT GMBH (DE) | 2019-02-07 | — | — | US | disclosed |
| WO-2016102040-A1 | CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS | MERCK PATENT GMBH (DE) | 2016-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230046046-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2C19, ESR1 | ALOX5 2450/4885KDM4E 2646/4885ATM 3069/4885 |
| US-20190044071-A1 | CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS | BRD3, BRPF3, DDT | ALOX5 1636/4885KDM4E 2631/4885ATM 3655/4885 |
| US-20230159434-A1 | MATERIALS FOR ELECTRONIC DEVICES | OCIAD2, AOC2, OCIAD1 | ALOX5 668/4885KDM4E 1802/4885ATM 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.