⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069517 | 0.89 | — | — | |
| SCHEMBL117305 | 0.86 | — | — | |
| SCHEMBL10069519 | 0.85 | — | — | |
| SCHEMBL10069518 | 0.84 | — | — | |
| SCHEMBL178900 | 0.79 | MEN1 (0.59) | — | |
| SCHEMBL118375 | 0.77 | — | — | |
| SCHEMBL117303 | 0.77 | — | — | |
| SCHEMBL27633641 | 0.75 | MEN1 (0.69) | — | |
| SCHEMBL117316 | 0.74 | — | — | |
| SCHEMBL117310 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058133-A1 | INHIBITION OF TRNA SYNTHETASES AND THERAPEUTIC APPLICATIONS THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-08 | — | — | US | disclosed |