Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.58 |
| ▸ | BCHE | P06276 | 4/20 | 0.58 |
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995708 | 0.85 | MEN1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL13995845 | 0.85 | MEN1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL2919519 | 0.84 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MITFLMNA | |
| SCHEMBL5695121 | 0.83 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9416002 | 0.81 | ATM (0.63) | MEN1KMT2AALDH1A1CHRM2GRIN1 | |
| SCHEMBL4918396 | 0.80 | CHRM2 (0.79) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL11102216 | 0.79 | MEN1 (0.59) | MEN1KMT2AALDH1A1MITFLMNA | |
| SCHEMBL15969133 | 0.79 | APLNR (0.73) | MEN1KMT2ATSHR | |
| SCHEMBL7376858 | 0.79 | APLNR (0.73) | MEN1KMT2ATSHR | |
| SCHEMBL4393397 | 0.79 | APLNR (0.73) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100358893-C | Certain novel imidazopyridines and uses thereof | ASTRAZENECA AB (SE) | 2008-01-02 | — | — | CN | claimed |
| CN-1684964-A | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2005-10-19 | — | — | CN | claimed |
| CN-100358893-C | Certain novel imidazopyridines and uses thereof | ASTRAZENECA AB (SE) | 2008-01-02 | — | — | CN | disclosed |
| CN-1684964-A | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2005-10-19 | — | — | CN | disclosed |