Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26078344 | 0.72 | ADRA1A (0.55) | TAAR1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL954867 | 0.68 | TAAR1 (0.70) | TAAR1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL17887759 | 0.67 | ADRA1A (0.51) | TAAR1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL26078346 | 0.67 | ADRA1A (0.51) | TAAR1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL954203 | 0.66 | TAAR1 (0.54) | TAAR1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL26078566 | 0.64 | TAAR1 (0.68) | TAAR1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL953083 | 0.64 | TAAR1 (0.68) | TAAR1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL953100 | 0.63 | TAAR1 (0.62) | TAAR1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL26078582 | 0.63 | TAAR1 (0.55) | TAAR1ADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL26078478 | 0.63 | NISCH (0.59) | TAAR1ADRA1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016105448-A1 | IMIDAZOLINE RECEPTOR TYPE 1 LIGANDS FOR USE AS THERAPEUTICS | RIDEOUT DARRYL (US) | 2016-06-30 | — | — | WO | disclosed |