Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.47 |
| ▸ | GLP1R | P43220 | 4/20 | 0.42 |
| ▸ | SCTR | P47872 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 9/20 | 0.42 |
| ▸ | NPY1R | P25929 | 5/20 | 0.42 |
| ▸ | NPY2R | P49146 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17887903 | 0.92 | NPY4R (0.42) | C5AR1GLP1RSCTRNPY4RNPY1R | |
| SCHEMBL29736307 | 0.92 | C5AR1 (0.52) | C5AR1GLP1RSCTRKEAP1PRMT1 | |
| SCHEMBL31496391 | 0.90 | C5AR1 (0.49) | C5AR1GLP1RSCTRNPY4RNPY1R | |
| SCHEMBL30148949 | 0.89 | NPY4R (0.37) | C5AR1GLP1RSCTRNPY4RNPY1R | |
| SCHEMBL30920012 | 0.87 | NPY4R (0.47) | C5AR1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL6710592 | 0.87 | NPY4R (0.51) | C5AR1GLP1RSCTRNPY4RNPY1R | |
| SCHEMBL9551329 | 0.87 | C5AR1 (0.47) | C5AR1GLP1RSCTRNPY4RNPY1R | |
| SCHEMBL6710584 | 0.87 | NPY4R (0.51) | C5AR1GLP1RSCTRNPY4RNPY1R | |
| SCHEMBL9551332 | 0.87 | C5AR1 (0.46) | C5AR1GLP1RSCTRNPY4RNPY1R | |
| SCHEMBL31088231 | 0.86 | NPY4R (0.49) | C5AR1NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016105448-A1 | IMIDAZOLINE RECEPTOR TYPE 1 LIGANDS FOR USE AS THERAPEUTICS | RIDEOUT DARRYL (US) | 2016-06-30 | — | — | WO | disclosed |