SCHEMBL29736307

CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	C5AR1	P21730	1/20	0.52

▸	GLP1R	P43220	15/20	0.50

▸	SCTR	P47872	1/20	0.50

▸	KEAP1	Q14145	1/20	0.46

▸	PRMT1	Q99873	1/20	0.45

▸	GCGR	P47871	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17887955	0.92	C5AR1 (0.47)	C5AR1GLP1RSCTRKEAP1PRMT1
SCHEMBL31496391	0.91	C5AR1 (0.49)	C5AR1GLP1RSCTRKEAP1
SCHEMBL30680486	0.90	NPY4R (0.48)	C5AR1GLP1RSCTRKEAP1
SCHEMBL30645268	0.90	C5AR1 (0.42)	C5AR1GLP1RSCTRKEAP1PRMT1
SCHEMBL31410887	0.87	GLP1R (0.57)	GLP1RSCTRKEAP1
SCHEMBL30804657	0.86	GLP1R (0.60)	GLP1RSCTRGCGR
SCHEMBL29736147	0.86	KEAP1 (0.47)	C5AR1GLP1RSCTRKEAP1
SCHEMBL30645275	0.86	GLP1R (0.44)	GLP1RSCTR
SCHEMBL30645274	0.86	GLP1R (0.48)	GLP1RSCTR
SCHEMBL30645272	0.85	NPY4R (0.49)	C5AR1GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11365217-B2	Peptides for treating telomere dysfunction-associated diseases and uses thereof	HANGZHOU DUANLI BIOTECHNOLOGY COMPANY LIMITED (CN)	2022-06-21	—	—	US	disclosed