Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GLI1 | P08151 | 1/20 | 0.42 |
| ▸ | GLI2 | P10070 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431747 | 0.85 | APP (0.63) | TRPV1APPBCHEACHE | |
| SCHEMBL17889101 | 0.85 | HPGD (0.56) | CXCL8HPGDGLI1GLI2ALOX15 | |
| SCHEMBL4418613 | 0.85 | HPGD (0.56) | CXCL8HPGDGLI1GLI2ALOX15 | |
| SCHEMBL3817985 | 0.85 | APP (0.63) | TRPV1APPBCHEACHE | |
| Hydrochloric Acid SCHEMBL4421826 | 0.84 | APP (0.62) | TRPV1APPBCHEACHE | |
| Hydrochloric Acid SCHEMBL4743230 | 0.84 | APP (0.62) | TRPV1APPBCHEACHE | |
| Hydrochloric Acid SCHEMBL4743234 | 0.84 | APP (0.62) | TRPV1APPBCHEACHE | |
| SCHEMBL17906293 | 0.82 | CXCL8 (0.50) | CXCL8HPGDGLI1GLI2ALOX15 | |
| SCHEMBL4428458 | 0.81 | CXCL8 (0.49) | CXCL8HPGDGLI1GLI2ALOX15 | |
| SCHEMBL17889085 | 0.81 | CXCL8 (0.52) | CXCL8HPGDGLI1GLI2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366018-B1 | OMEGA-AMINOALKYLAMIDES OF (R)-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | DOMPÉ FARMACEUTICI S P A (IT) | 2016-07-06 | — | — | EP | claimed |
| EP-1366018-B1 | OMEGA-AMINOALKYLAMIDES OF (R)-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | DOMPÉ FARMACEUTICI S P A (IT) | 2016-07-06 | — | — | EP | disclosed |