Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GLI1 | P08151 | 2/20 | 0.46 |
| ▸ | GLI2 | P10070 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17889085 | 0.90 | CXCL8 (0.52) | CXCL8ALOX15HPGDGLI1GLI2 | |
| SCHEMBL4418613 | 0.88 | HPGD (0.56) | CXCL8ALOX15HPGDGLI1GLI2 | |
| SCHEMBL17889101 | 0.88 | HPGD (0.56) | CXCL8ALOX15HPGDGLI1GLI2 | |
| SCHEMBL17906293 | 0.86 | CXCL8 (0.50) | CXCL8ALOX15HPGDGLI1GLI2 | |
| SCHEMBL17889135 | 0.85 | GLI1 (0.64) | CXCL8HPGDGLI1GLI2ALDH1A1 | |
| SCHEMBL4910072 | 0.85 | GLI1 (0.64) | CXCL8HPGDGLI1GLI2ALDH1A1 | |
| SCHEMBL4428462 | 0.85 | CXCL8 (0.49) | CXCL8ALOX15HPGDGLI1GLI2 | |
| SCHEMBL4428458 | 0.85 | CXCL8 (0.49) | CXCL8ALOX15HPGDGLI1GLI2 | |
| SCHEMBL17889093 | 0.81 | CXCL8 (0.48) | CXCL8ALOX15HPGDGLI1GLI2 | |
| SCHEMBL11624162 | 0.81 | GLI1 (0.61) | CXCL8HPGDGLI1GLI2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366018-B1 | OMEGA-AMINOALKYLAMIDES OF (R)-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | DOMPÉ FARMACEUTICI S P A (IT) | 2016-07-06 | — | — | EP | disclosed |