Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 0.72 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.72 |
| ▸ | ABL1 | P00519 | 1/20 | 0.68 |
| ▸ | LCK | P06239 | 1/20 | 0.68 |
| ▸ | LYN | P07948 | 1/20 | 0.68 |
| ▸ | SRC | P12931 | 1/20 | 0.68 |
| ▸ | CSK | P41240 | 1/20 | 0.68 |
| ▸ | BTK | Q06187 | 1/20 | 0.68 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 8/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.67 |
| ▸ | TUBB | P07437 | 5/20 | 0.67 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.67 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.67 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.67 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.67 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.67 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17890297 | 1.00 | KMT2A (1.00) | KMT2AMEN1PSMD14ABL1LCK | |
| SCHEMBL6230728 | 0.88 | KMT2A (0.82) | KMT2AMEN1PSMD14ABL1LCK | |
| SCHEMBL6230731 | 0.88 | KMT2A (0.82) | KMT2AMEN1PSMD14ABL1LCK | |
| SCHEMBL17890024 | 0.81 | TUBB4A (0.77) | KMT2AMEN1PSMD14ABL1LCK | |
| SCHEMBL17890026 | 0.81 | TUBB4A (0.77) | KMT2AMEN1PSMD14ABL1LCK | |
| SCHEMBL1508832 | 0.80 | TUBB4A (1.00) | KMT2AMEN1NPC1RAB9ATUBB4A | |
| SCHEMBL1508835 | 0.80 | TUBB4A (1.00) | KMT2AMEN1NPC1RAB9ATUBB4A | |
| SCHEMBL6977895 | 0.77 | PSEN1 (1.00) | KMT2AMEN1PSMD14NPC1RAB9A | |
| SCHEMBL16017996 | 0.77 | GUSB (0.76) | KMT2ANPC1RAB9ACASP3SENP7 | |
| SCHEMBL10684960 | 0.77 | KMT2A (0.62) | KMT2AMEN1PSMD14TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951029-B2 | Styryl quinazoline derivatives as pharmaceutically active agents | VICHEM CHEMIE KUTATÓ KFT. (HU) | 2018-04-24 | — | — | US | disclosed |
| US-20160194291-A1 | STYRYL QUINAZOLINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE AGENTS | VICHEM CHEMIE KUTATÓ KFT. (HU) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194291-A1 | STYRYL QUINAZOLINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE AGENTS | FLT3, BCR, STK3 | KMT2A 3110/4885MEN1 3840/4885PSMD14 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.