Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.82 |
| ▸ | NPC1 | O15118 | 8/20 | 0.82 |
| ▸ | RAB9A | P51151 | 8/20 | 0.82 |
| ▸ | MEN1 | O00255 | 6/20 | 0.82 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.70 |
| ▸ | TUBB | P07437 | 5/20 | 0.70 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.70 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.70 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.70 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.70 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.70 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.70 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.70 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.70 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.70 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.70 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.70 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.70 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.70 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230731 | 1.00 | KMT2A (0.82) | KMT2ANPC1RAB9AMEN1TUBB4A | |
| SCHEMBL17890294 | 0.88 | KMT2A (1.00) | KMT2ANPC1RAB9AMEN1TUBB4A | |
| SCHEMBL17890297 | 0.88 | KMT2A (1.00) | KMT2ANPC1RAB9AMEN1TUBB4A | |
| SCHEMBL27771769 | 0.84 | KMT2A (0.61) | KMT2ANPC1RAB9AMEN1TUBB4A | |
| SCHEMBL17890026 | 0.84 | TUBB4A (0.77) | KMT2ANPC1RAB9AMEN1TUBB4A | |
| SCHEMBL17890024 | 0.84 | TUBB4A (0.77) | KMT2ANPC1RAB9AMEN1TUBB4A | |
| SCHEMBL1589647 | 0.82 | PSEN1 (0.65) | KMT2ANPC1RAB9AMEN1TUBB4A | |
| SCHEMBL7625703 | 0.82 | PSEN1 (0.65) | KMT2ANPC1RAB9AMEN1TUBB4A | |
| SCHEMBL6977895 | 0.81 | PSEN1 (1.00) | KMT2ANPC1RAB9AMEN1PSMD14 | |
| SCHEMBL1508832 | 0.80 | TUBB4A (1.00) | KMT2ANPC1RAB9AMEN1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900219-B2 | ABCA-1 elevating compounds | CV THERAPEUTICS, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1513534-A2 | COMPOUNDS FOR INCREASING ABCA-1 EXPRESSION USEFUL FOR TREATING CORONARY ARTERY DISEASE AND ATHEROSCLEROSIS | CV THERAPEUTICS, INC. (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20030220356-A1 | ABCA-1 elevating compounds | CV THERAPEUTICS, INC. | 2003-11-27 | — | — | US | disclosed |
| WO-2003084544-A2 | COMPOUNDS DOR INCREASING ABCA-1 EXPRESSION USEFUL FOR TREATING CORONARY ARTERY DISEASE AND ATHEROSCLEROSIS | CV THERAPEUTICS, INC. (US) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220356-A1 | ABCA-1 elevating compounds | ABCD3, ABCE1, ABCB4 | KMT2A 3796/4885NPC1 6/4885RAB9A 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.